The James Webb Space Telescope: This is the most powerful and advanced telescope ever created, and it captured the first ever photos of distant galaxies and stars in stunning detail1.

AlphaFold2, RoseTTAFold, and trRosettaX-Single: These are algorithms that can predict the 3D structure of a protein molecule from its amino-acid sequence, which is crucial for understanding how proteins function and interact2.

Synthetic biology: This is the field of engineering biological systems to produce biomolecules and materials, such as insulin, leather, and spider silk, without using animals or plants2.

The Einstein shape: This is a new shape of matter that was predicted by Albert Einstein in 1915, but only observed for the first time in 2023. It is a ring of light that bends around a massive object, such as a black hole1.

Zellerfeld 3D-printed shoes: These are shoes that are made from recycled plastic and can be customized and printed on demand, reducing waste and carbon footprint1.

Medivis SurgicalAR: This is a device that uses augmented reality to help surgeons visualize the anatomy and pathology of a patient in real time, improving accuracy and safety.

OpenAI Dall-E 3: This is an artificial intelligence system that can generate realistic images from text descriptions, such as “a cat wearing a hat” or "a skyscraper made of cheese".

The Good Cup: This is a reusable coffee cup that has a lid made from biodegradable material, which can be composted or eaten after use.

Project Gutenberg Open Audiobook Collection: This is a collection of over 10,000 free audiobooks that are created from public domain books using text-to-speech technology.

AlertCalifornia and Cal Fire AI Wildfire Detector: These are systems that use artificial intelligence and sensors to detect and alert people about wildfires, helping to prevent and contain them.

Digital Travel Credentials: These are electronic passports that can be stored on a smartphone or a wearable device, making travel more convenient and secure.

New species: Several new and rare species of animals and plants were discovered or rediscovered in 2023, such as the blue-eyed black lemur, the giant siphonophore, and the pink fairy armadillo.